The 2004 ASM Biodefense Research Meeting, held March 7-10, 2004, in Baltimore, Maryland, continued the success of ASM's first Biodefense Meeting held in 2003 as an important scientific research event. The meeting featured an impressive line-up of speakers, poster presentations and pre-meeting workshops, and was extremely well-received by the over 700 scientists in attendance.
| Sunday, March 7, 2004 |
| Time |
Session |
Presenters |
| 8:00 am-12:00 pm |
Bio, PhRMA, FDA Workshop |
|
| 12:00-2:00 pm |
NIH Workshop I |
|
| 12:00-2:00 pm |
DTRA and Dept. of Homeland Security Workshop |
|
| 2:00-4:00 pm |
CDC Workshop |
|
| 2:00-4:00 pm |
NIH Workshop II |
|
|
| |
Opening Session |
|
| 6:00 pm |
Welcome Remarks |
Thomas E. Shenk, Ph.D., ASM President
Gail H. Cassell, Ph.D., Chair, 2004 Biodefense Meeting Program Committee |
| 6:15-7:15 pm |
Panel Discussion: Science and Technology for Security |
Moderator: Gerald R. Fink, Ph.D., MIT, Cambridge, MA
Participants: TBA |
| 7:15-8:15 pm |
Progress in Biodefense Research |
Anthony S. Fauci, M.D., NIAID, NIH |
| Monday, March 8, 2004 |
| Time |
Session |
Presenters |
| |
Poster Session |
|
| 8:30 am-7:00 pm |
Posters on Display |
|
| 5:00-7:00 pm |
Presentations by Authors |
|
|
| |
Keynote Session |
|
| 8:30-9:30 am |
RNA Biology and Implications for Development of Novel Therapies |
Phillip A. Sharp, Ph.D., MIT, Cambridge, MA |
|
| |
Symposium Session |
|
| 9:30 am-12:00 pm |
Advanced Technology in Countermeasure Development |
Chair, Leroy Hood, M.D., Ph.D., Inst. for Systems Biology, Seattle, WA |
| |
CATERPILLER and TLR Genes and Their Ablation by RNAi as a Tool for Rapid Intervention in Biodefense
|
Jenny P.Y. Ting, Ph.D., Univ. of North Carolina, Chapel Hill, NC |
| |
Advanced Laser and Biochip Technologies for Biodefense
|
Tuan Vo-Dinh, Ph.D., Oak Ridge National Lab., Oak Ridge, TN |
| |
Computational Tools for Biological Analysis
|
Hamid Bolouri, Ph.D., Inst. for Systems Biology, Seattle, WA |
| |
Directed Evolution |
Gerald F. Joyce, M.D., Ph.D., Scripps Res. Inst., La Jolla, CA |
| |
Chemistry and Genomics |
Jon Clardy, Ph.D., Harvard Univ. Sch. of Med., Boston, MA |
|
| |
Keynote Session |
|
| 1:30-2:30 pm |
Prions as Zoonotic Disease |
Stanley Prusiner, M.D., Univ. of San Fransisco, CA |
|
| |
Symposium Session |
|
| 2:30-5:00 pm |
Countermeasure Development for Viral Zoonoses
|
Chair, Peter B. Jahrling, Ph.D., USAMRIID, Frederick, MD |
| |
Immune Evasion as a Critical Strategy of Virulent Orthopoxviruses
|
Grant McFadden, Ph.D., Robarts Research Inst., London, ON, Canada |
| |
Contemporary Approaches to Vaccines for "High Hazard" Viruses
|
Connie S. Schmaljohn, Ph.D., USAMRIID, Frederick, MD |
| |
Effective Intervention in Viral Hemorrhagic Fever Pathogenesis via Coagulation Cascade Inhibitors
|
Thomas Geisbert, Ph.D., USAMRIID, Frederick, MD |
| |
Vaccine Development Strategies for Ebola and other Viral Hemorrhagic Fever Agents Using Reverse Genetics |
Heinz Feldmann, M.D., Bureau of Microbiology, Winnipeg, Manitoba, Canada |
| Tuesday, March 9, 2004 |
| Time |
Session |
Presenters |
| |
Poster Session |
|
| 8:30 am-7:00 pm |
Posters on Display |
|
| 5:00-7:00 pm |
Presentations by Authors |
|
|
| |
Keynote Session |
|
| 8:30-9:30 am |
Mice, Microbes and Models of Infection |
Robert C. Balling, Jr., Ph.D., Arizona State Univ., Tempe, AZ |
|
| |
Symposium Session |
|
| 9:30 am-12:00 pm |
Novel Models for Mapping Susceptibility and Immune Modulatory Genes in Infectious Diseases and Biodefense and Ultimately Application of the FDA Animal Rule
|
Chair, Malak Y. Kotb, Ph.D., Univ. of Tennessee, Memphis, TN |
| |
The Infectious Disease Phenome Project: Development of Advanced Recombinant Inbred Mice and Novel Technology to Map Susceptibility and Immunity Genes
|
Robert Williams, Ph.D., Univ. of Tennessee, Memphis, TN |
| |
Identification of Anthrax Immunity Gene (Kiflc) Using Recombinant Inbred Mice
|
William F. Dietrich, Ph.D., Harvard Med. School, Boston, MA |
| |
Partially and Fully Humanized Mouse Models to Study Immune Response to Infectious Agents
|
Leonard D. Schultz, Ph.D., Jackson Lab., Bar Harbour, ME |
| |
West Nile Virus |
Margo A. Brinton, Ph.D., Georgia State Univ., Atlanta, GA |
| |
Relevant Models and FDA Approval via the "Animal Rule" |
FDA speaker TBA |
|
| |
Keynote Session |
|
| 1:30-2:30 pm |
Application of Reverse Genetics to Antibody Structure and Function: Lessons Learned from HIV |
Dennis Burton, Ph.D., Scripps Res. Inst., La Jolla, CA |
|
| |
Symposium Session |
|
| 2:30-5:00 pm |
Advances in B-Cell Biology: Implications for Countermeasure Development
|
Chair, Matthew D. Scharrf, M.D., Albert Einstein Coll. of Med., Bronx, NY |
| |
The Immunobiology of B.anthracis with Emphasis on Spore-Host Interactions and Antibody Development
|
John F. Kearney, Ph.D., Univ. of Alabama, Birmingham, AL |
| |
Title TBA |
James E. Crowe, M.D., Vanderbilt Univ., Nashville, TN |
| |
Prophylactic and Therapeutic Uses of Antibody |
Arturo Casadevall, M.D., Ph.D., Albert Einstein Coll. of Med., Bronx, NY |
| |
Long-Term B-Cell Memory of Humans after Smallpox Vaccination |
Shane Crotty, Ph.D., La Jolla Inst. for Allergy and Immunology, La Jolla, CA |
| Wednesday, March 10, 2004 |
| Time |
Session |
Presenters |
| |
Keynote Session |
|
| 8:30-9:30 am |
Realities of Vaccine Development |
Harry B. Greenberg, M.D., Stanford Univ., CA |
|
| |
Symposium Session |
|
| 9:30 am-12:00 pm |
Vaccine Strategies with Emphasis on Gastrointestinal Pathogens
|
Chair, Kathryn Zoon, Ph.D., NCI, NIH, Bethesda, MD |
| |
Unique Role of Dendritic Cells and Immune Responsiveness in the Gastrointestinal Tract
|
Brian L. Kelsall, M.D., NIAID, NIH, Bethesda, MD |
| |
Bacterial Pathogenesis |
James B. Kaper, Ph.D., Univ. of Maryland Sch. of Med., Baltimore, MD |
| |
Viral Pathogens |
Mary K. Estes, Ph.D., Baylor Coll. of Med., Houston, TX |
| |
Systematic Identification of Research Gaps for Food and Waterborne Pathogens |
Bruce Hope, Ph.D., Oregon Dept. of Environmental Quality, Portland, OR |
|
| |
Keynote Session |
|
| 1:30-2:30 pm |
The Complex Genetic Network Controlling a Bacterial Cell Cycle: Circuit Nodes as Targets for Small Molecule Antibiotics |
Lucy Shapiro, Ph.D., Stanford Univ. Sch. of Med., CA |
|
| |
Symposium Session |
|
| 2:30-5:00 pm |
Host/Pathogen Regulatory Networks |
Chair, Richard A. Young, Ph.D., Whitehead Inst. for Biomedical Research, MIT, Cambridge, MA |
| |
Pathogen Regulatory Networks and Importance of Inate Immunity
|
Samuel I. Miller, M.D., Univ. of Washington, Seattle, WA |
| |
Host Regulatory Netwrks Controlling Fraciscella tularensis
|
Karen L. Elkins, Ph.D., CBER, FDA, Rockville, MD |
| |
Bacterial Intracellular Communities in Bacterial Infections
|
Scott J. Hultgren, Ph.D., Washington Univ. Sch. of Med., St. Louis, MO |
| |
Effector Proteins and Proteases |
Jack Dixon, Ph.D., Univ. of California, La Jolla, CA |
| |
Type III Secretory Proteins |
Jorge E. Galan, DVM, Yale Sch. of Med., New Haven, CT |
|
